Revisiting the role of Dcc in visual system development with a novel eye clearing method
The Deleted in Colorectal Carcinoma (Dcc) receptor plays a critical role in optic nerve development.Whilst Dcc is expressed postnatally in the eye, its function remains unknown as Dcc knockouts die at birth.To circumvent this drawback, we generated an eye-specific Dcc mutant.To study the organization of the retina and visual projections in these mi